Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.54 |
| ▸ | FNTB | P49356 | 9/20 | 0.54 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7996549 | 1.00 | FNTA (0.54) | FNTAFNTBPGGT1BPDK1PDK2 | |
| SCHEMBL7983222 | 0.93 | FNTA (0.60) | FNTAFNTBPGGT1BCA1CA2 | |
| SCHEMBL7983219 | 0.93 | FNTA (0.60) | FNTAFNTBPGGT1BCA1CA2 | |
| SCHEMBL7994798 | 0.80 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL7994795 | 0.80 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7996273 | 0.79 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7996274 | 0.79 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8869572 | 0.78 | FNTA (0.53) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8869802 | 0.77 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8869811 | 0.77 | FNTA (0.49) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5631280-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |