Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000632 | 1.00 | HDAC6 (0.32) | HDAC6HDAC1HDAC2SLC22A6MAPT | |
| SCHEMBL3475650 | 0.81 | MEN1 (0.32) | HDAC6HDAC1HDAC2SLC22A6 | |
| SCHEMBL8000626 | 0.80 | HDAC6 (0.34) | HDAC6HDAC1HDAC2SLC22A6CYP2D6 | |
| SCHEMBL7996579 | 0.80 | HDAC6 (0.34) | HDAC6HDAC1HDAC2SLC22A6CYP2D6 | |
| SCHEMBL7351512 | 0.79 | AAK1 (0.34) | HDAC6HDAC1HDAC2CYP2D6PGD | |
| SCHEMBL10473406 | 0.79 | AAK1 (0.34) | HDAC6HDAC1HDAC2CYP2D6PGD | |
| SCHEMBL28532726 | 0.73 | MEN1 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL16899123 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL27603675 | 0.72 | CYP1A2 (0.35) | HDAC6HDAC1HDAC2 | |
| SCHEMBL1564464 | 0.72 | CYP1A2 (0.35) | HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066530-A1 | URETHANE β-AMINO ACID β-CARBOXYANHYDRIDES, PREPARATION METHOD AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-09-13 | — | — | WO | disclosed |