SCHEMBL799687

SCHEMBL799687

Cc1ccc(C)c(N)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31083628 1.00
SCHEMBL17551 0.78
SCHEMBL361501 0.78
SCHEMBL29599682 0.78
SCHEMBL2843454 0.74
SCHEMBL14108670 0.74
SCHEMBL17298252 0.74
SCHEMBL21047964 0.74
SCHEMBL222185 0.74
SCHEMBL6984571 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615839-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE Bristol-Myers Squibb Company (US) 2025-09-17 EP disclosed
US-20240180886-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-06-06 US disclosed
WO-2024102794-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-05-16 WO disclosed
US-11858915-B2 Polo like kinase 4 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2024-01-02 US disclosed
EP-3956320-B1 DIHYDROOROTATE DEHYDROGENASE INHIBITORS JANSSEN BIOTECH INC (US) 2023-11-29 EP disclosed
US-20230365529-A1 PARP7 INHIBITORS GILEAD SCIENCES, INC. 2023-11-16 US disclosed
WO-2022213204-A9 CARBOXAMIDE PYROLOPYRAZINE AND PYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF MYT1 AND USE THEREOF IN THE TREATMENT OF CANCER REPARE THERAPEUTICS INC. (CA) 2023-11-16 WO disclosed
US-11814391-B2 Macrocyclic compounds for the treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2023-11-14 US disclosed
US-20230331740-A1 BICYCLIC HETEROCYCLYL DERIVATIVES AS IRAK4 INHIBITORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2023-10-19 US disclosed
US-20230322803-A1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2023-10-12 US disclosed
US-6495672-B1 DIAGNOSIS AND SEPARATION THROUGH TRIPLEX BINDING ISIS PHARMACEUTICALS, INC. 2002-12-17 US disclosed
US-6447998-B1 METHOD OF DETECTING THE PRESENCE, ABSENCE OR AMOUNT OF A PARTICULAR DNA DUPLEX IN A SAMPLE SUSPECTED OF CONTAINING DNA COMPRISING CONTACTING THE SAMPLE WITH AN OLIGOMER OF UNDER CONDITIONS WHEREIN A TRIPLE HELIX IS FORMED BETWEEN THE ISIS PHARMACEUTICALS, INC. 2002-09-10 US disclosed
WO-2002064211-A1 THROMBIN INHIBITORS MERCK & CO., INC. (US) 2002-08-22 WO disclosed
EP-1017393-A4 PYRAZINONE THROMBIN INHIBITORS MERCK & CO INC (US) 2002-01-23 EP disclosed
EP-1017393-A1 PYRAZINONE THROMBIN INHIBITORS Merck & Co., Inc. (US) 2000-07-12 EP disclosed
US-6011038-A Pyrazinone thrombin inhibitors MERCK & CO., INC. (US) 2000-01-04 US disclosed
WO-1999011267-A1 PYRAZINONE THROMBIN INHIBITORS MERCK & CO., INC. (US) 1999-03-11 WO disclosed
EP-0135833-B1 METHOD FOR THE PREPARATION OF 2-AMINO-ALKYLPYRIDINES BAYER AG (DE) 1987-10-28 EP disclosed
US-4628097-A Process for the preparation of 2-amino-alkylpyridines BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
US-3995044-A Pyridine carboxylic acid amides for mycobacterium infections BAYER AKTIENGESELLSCHAFT (DT) 1976-11-30 US disclosed