Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998649 | 0.91 | NPC1 (0.53) | NPC1MEN1KMT2ATYMSHTT | |
| SCHEMBL8004788 | 0.89 | NPC1 (0.51) | NPC1MEN1KMT2ATYMSALDH1A1 | |
| SCHEMBL8004847 | 0.88 | NPC1 (0.50) | NPC1MEN1KMT2ATYMSHTT | |
| SCHEMBL8076784 | 0.88 | NPC1 (0.50) | NPC1MEN1KMT2ATYMSHTT | |
| SCHEMBL8000946 | 0.88 | NPC1 (0.50) | NPC1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8004403 | 0.88 | NPC1 (0.50) | NPC1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8076775 | 0.85 | NPC1 (0.47) | NPC1MEN1KMT2ATYMSALDH1A1 | |
| SCHEMBL8000796 | 0.84 | NPC1 (0.54) | NPC1MEN1KMT2ATYMSKDM4E | |
| SCHEMBL7997061 | 0.84 | TYMS (0.47) | NPC1MEN1KMT2ATYMSHTT | |
| SCHEMBL8001033 | 0.84 | TYMS (0.47) | NPC1MEN1KMT2ATYMSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |