Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SELP | P16109 | 6/20 | 0.46 |
| ▸ | SELE | P16581 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997394 | 1.00 | MEN1 (0.49) | MEN1KMT2ASELPSELETAS1R3 | |
| SCHEMBL8194916 | 0.88 | SELP (0.58) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL8194911 | 0.88 | SELP (0.58) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL7997425 | 0.87 | MEN1 (0.46) | MEN1KMT2ASELPSELETAS1R3 | |
| SCHEMBL7997432 | 0.87 | MEN1 (0.46) | MEN1KMT2ASELPSELETAS1R3 | |
| SCHEMBL7995394 | 0.84 | SELP (0.67) | MEN1KMT2ASELPSELETAS1R3 | |
| SCHEMBL7995405 | 0.84 | SELP (0.67) | MEN1KMT2ASELPSELETAS1R3 | |
| SCHEMBL8000298 | 0.84 | SELP (0.53) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL7995368 | 0.84 | SELP (0.53) | MEN1KMT2ASELPSELEPTPN1 | |
| SCHEMBL7993112 | 0.82 | MEN1 (0.54) | MEN1KMT2ASELPSELEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |