Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001262 | 0.96 | CYP1A2 (0.47) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL7997229 | 0.93 | CNR2 (0.49) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL8001046 | 0.93 | CNR2 (0.49) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL7988323 | 0.93 | CNR1 (0.47) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL7988306 | 0.92 | CYP1A2 (0.45) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL7997589 | 0.91 | MAPT (0.48) | CYP1A2CNR1ACHECNR2MEN1 | |
| SCHEMBL7998038 | 0.91 | MAPT (0.48) | CYP1A2CNR1ACHECNR2MEN1 | |
| SCHEMBL7998812 | 0.90 | CYP1A2 (0.48) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL8004909 | 0.90 | CYP1A2 (0.48) | CYP1A2CNR1ACHECNR2CYSLTR2 | |
| SCHEMBL8001967 | 0.89 | CYP1A2 (0.47) | CYP1A2CNR1ACHECNR2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |