Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA4 | P22748 | 6/20 | 0.34 |
| ▸ | CA5A | P35218 | 6/20 | 0.34 |
| ▸ | CA7 | P43166 | 6/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514887 | 1.00 | TSHR (0.44) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL8013182 | 1.00 | TSHR (0.44) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL7515678 | 1.00 | TSHR (0.44) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL7999373 | 1.00 | TSHR (0.44) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL8006528 | 0.93 | ANTXR2 (0.42) | TSHRCA12CA1CA2ANTXR2 | |
| SCHEMBL7996393 | 0.93 | ANTXR2 (0.42) | TSHRCA12CA1CA2ANTXR2 | |
| SCHEMBL7996388 | 0.93 | ANTXR2 (0.42) | TSHRCA12CA1CA2ANTXR2 | |
| SCHEMBL8002963 | 0.83 | TSHR (0.35) | TSHR | |
| SCHEMBL7985818 | 0.82 | ELANE (0.32) | ELANE | |
| SCHEMBL7995825 | 0.82 | ELANE (0.32) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040433-A | Sulfinyl hexose derivatives useful for glycosylation | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0901629-A4 | CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD | UNIV PRINCETON (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0901629-A1 | CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD | PRINCETON UNIVERSITY (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997035202-A1 | CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD | PRINCETON UNIVERSITY (US) | 1997-09-25 | — | — | WO | disclosed |