Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001268 | 0.96 | MEN1 (0.52) | MEN1KMT2AMAPTTYMSCNR2 | |
| SCHEMBL8001054 | 0.92 | MEN1 (0.51) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL8000665 | 0.92 | MEN1 (0.51) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL8000975 | 0.90 | MEN1 (0.49) | MEN1KMT2ATYMSCNR2SMN1; SMN2 | |
| SCHEMBL8000531 | 0.89 | MEN1 (0.59) | MEN1KMT2AMAPTTYMSHTT | |
| SCHEMBL8074612 | 0.89 | MAPT (0.48) | MEN1KMT2AMAPTCNR2 | |
| SCHEMBL7988572 | 0.88 | MAPT (0.47) | MEN1KMT2AMAPTTYMSCNR2 | |
| SCHEMBL8004179 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTTYMSHTT | |
| SCHEMBL8001073 | 0.88 | MEN1 (0.51) | MEN1KMT2ATYMSCNR2SMN1; SMN2 | |
| SCHEMBL8004176 | 0.87 | MEN1 (0.47) | MEN1KMT2AMAPTTYMSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |