Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948429 | 0.91 | DNMT1 (0.50) | DNMT1EHMT2HRH1KCNH2ADRB2 | |
| SCHEMBL8948400 | 0.78 | DNMT1 (0.58) | DNMT1EHMT2HRH1KCNH2TEAD1 | |
| SCHEMBL8792457 | 0.78 | NPY2R (0.52) | DNMT1EHMT2HRH1KCNH2TEAD1 | |
| SCHEMBL8948348 | 0.77 | HRH1 (0.52) | DNMT1EHMT2HRH1KCNH2TEAD1 | |
| Hydrochloric Acid SCHEMBL8200558 | 0.76 | KCNH2 (0.67) | DNMT1EHMT2HRH1KCNH2KDM4E | |
| SCHEMBL8948477 | 0.76 | DNMT1 (0.61) | DNMT1EHMT2HRH1KCNH2GPR119 | |
| SCHEMBL7472446 | 0.75 | DNMT1 (0.58) | DNMT1EHMT2HRH1L3MBTL1KCNH2 | |
| SCHEMBL7243421 | 0.75 | CA12 (0.61) | ALDH1A1 | |
| SCHEMBL8908394 | 0.75 | DNMT1 (0.57) | DNMT1EHMT2HRH1KCNH2GPR119 | |
| SCHEMBL29434969 | 0.75 | DNMT1 (1.00) | DNMT1EHMT2HRH1HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912090-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED ARYL) HYDROXYMETHYL]PIPERIDINIUM SALTS | FMC CORP (US) | 2000-05-17 | — | — | EP | claimed |
| EP-0912090-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED ARYL) HYDROXYMETHYL]PIPERIDINIUM SALTS | FMC CORPORATION (US) | 1999-05-06 | — | — | EP | claimed |
| WO-1998000015-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED ARYL) HYDROXYMETHYL]PIPERIDINIUM SALTS | FMC CORPORATION (US) | 1998-01-08 | — | — | WO | claimed |