Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TNF | P01375 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983841 | 0.80 | SMN1; SMN2 (0.50) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8001463 | 0.79 | SMN1; SMN2 (0.49) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL2513699 | 0.78 | CYP11B1 (0.49) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7983835 | 0.77 | SMN1; SMN2 (0.47) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7994647 | 0.76 | SMN1; SMN2 (0.49) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7983909 | 0.76 | SMN1; SMN2 (0.49) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7995844 | 0.75 | SMN1; SMN2 (0.48) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7983724 | 0.75 | SMN1; SMN2 (0.55) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL30310275 | 0.74 | MAPK1 (0.69) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL28975960 | 0.74 | MAPK1 (0.69) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |