Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 12/20 | 0.42 |
| ▸ | ACHE | P22303 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710165 | 1.00 | HTT (0.45) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL7997918 | 1.00 | HTT (0.45) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL1710168 | 1.00 | HTT (0.45) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL6579165 | 0.96 | HTT (0.51) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL6579161 | 0.96 | HTT (0.51) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL6582144 | 0.94 | HTT (0.46) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL6582148 | 0.94 | HTT (0.46) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL27494189 | 0.94 | MEN1 (0.42) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL8000967 | 0.93 | HTT (0.44) | HTTHTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL8000672 | 0.93 | HTT (0.44) | HTTHTR1AHTR2CHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |