Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998032 | 1.00 | MEN1 (0.44) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL8000607 | 0.94 | MEN1 (0.42) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL8000601 | 0.94 | MEN1 (0.42) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL8001245 | 0.94 | MEN1 (0.40) | MEN1KMT2ATYMSHTTCNR2 | |
| SCHEMBL8001242 | 0.94 | MEN1 (0.40) | MEN1KMT2ATYMSHTTCNR2 | |
| SCHEMBL8002015 | 0.93 | MEN1 (0.39) | MEN1KMT2ATYMSHTTCNR2 | |
| SCHEMBL8002022 | 0.93 | MEN1 (0.39) | MEN1KMT2ATYMSHTTCNR2 | |
| SCHEMBL7997718 | 0.92 | NR1H4 (0.39) | MEN1KMT2ACNR2 | |
| SCHEMBL8004453 | 0.92 | NR1H4 (0.39) | MEN1KMT2ATYMS | |
| SCHEMBL7997745 | 0.92 | NR1H4 (0.39) | MEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |