Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626120 | 0.85 | FNTA (0.58) | FNTAFNTBMEN1KMT2APGGT1B | |
| SCHEMBL7626104 | 0.85 | FNTA (0.58) | FNTAFNTBMEN1KMT2APGGT1B | |
| SCHEMBL7623245 | 0.83 | FNTA (0.52) | FNTAFNTBKMT2APGGT1B | |
| SCHEMBL7623241 | 0.83 | FNTA (0.52) | FNTAFNTBKMT2APGGT1B | |
| SCHEMBL7622462 | 0.74 | FNTA (0.69) | FNTAFNTBMEN1KMT2AMME | |
| SCHEMBL7622474 | 0.74 | FNTA (0.69) | FNTAFNTBMEN1KMT2AMME | |
| SCHEMBL6056526 | 0.73 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL6056534 | 0.73 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL7837953 | 0.72 | SMN1; SMN2 (0.45) | MEN1KMT2A | |
| SCHEMBL7451211 | 0.72 | SMN1; SMN2 (0.45) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840605-A4 | COMPOUNDS USEFUL IN THE TREATMENT OF NEUROFIBROMATOSIS | UNIV CINCINNATI (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0840605-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEUROFIBROMATOSIS | University of Cincinnati (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997002817-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEUROFIBROMATOSIS | UNIVERSITY OF CINCINNATI (US) | 1997-01-30 | — | — | WO | disclosed |