Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 16/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12406950 | 1.00 | UGCG (0.66) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL13493071 | 1.00 | UGCG (0.66) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL1373500 | 0.92 | UGCG (0.79) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL12088025 | 0.92 | UGCG (0.79) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL7926312 | 0.92 | UGCG (0.79) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL1085010 | 0.92 | UGCG (0.79) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL3748105 | 0.92 | UGCG (0.79) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL1809813 | 0.90 | UGCG (0.64) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL7931481 | 0.90 | UGCG (0.64) | UGCGHTR1APTGS1OPRM1MEN1 | |
| SCHEMBL12406938 | 0.89 | UGCG (0.62) | UGCGHTR1APTGS1OPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117150-A2 | METHOD OF TREATING LUPUS WITH CERAMIDE DERIVATIVES | GENZYME CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2008150486-A2 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |