Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 13/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | PGR | P06401 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | IL6 | P05231 | 1/20 | 0.57 |
| ▸ | GLUL | P15104 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264554 | 0.94 | HIF1A (0.64) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL945988 | 0.93 | HIF1A (0.65) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL704875 | 0.91 | HIF1A (0.61) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL28926350 | 0.91 | HIF1A (0.55) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL28596717 | 0.91 | HIF1A (0.55) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL27748218 | 0.90 | HIF1A (0.61) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL7095395 | 0.90 | HIF1A (0.61) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL11068491 | 0.89 | HIF1A (0.62) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL27781029 | 0.89 | HIF1A (0.66) | HIF1ANR3C1HSD17B10PGRCYP3A4 | |
| SCHEMBL122048 | 0.89 | HIF1A (0.63) | HIF1ANR3C1HSD17B10PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831912-A4 | IMPROVED FORMULATION FOR CONTROLLED RELEASE OF DRUGS BY COMBINING HYDROPHILIC AND HYDROPHOBIC AGENTS | OCULEX PHARM INC (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0831912-A1 | IMPROVED FORMULATION FOR CONTROLLED RELEASE OF DRUGS BY COMBINING HYDROPHILIC AND HYDROPHOBIC AGENTS | OCULEX PHARMACEUTICALS, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996038174-A1 | IMPROVED FORMULATION FOR CONTROLLED RELEASE OF DRUGS BY COMBINING HYDROPHILIC AND HYDROPHOBIC AGENTS | OCULEX PHARMACEUTICALS, INC. (US) | 1996-12-05 | — | — | WO | disclosed |