Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 20/20 | 0.73 |
| ▸ | CCNE1 | P24864 | 20/20 | 0.73 |
| ▸ | CDK2 | P24941 | 20/20 | 0.73 |
| ▸ | CDK4 | P11802 | 16/20 | 0.71 |
| ▸ | CCND1 | P24385 | 16/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000202 | 0.94 | CCNE2 (0.68) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL7987271 | 0.86 | CCNE2 (0.85) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL5515366 | 0.86 | CCNE2 (0.82) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL5518134 | 0.86 | CCNE2 (0.82) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL7998034 | 0.86 | CCNE2 (0.82) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL7987334 | 0.86 | CCNE2 (0.81) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL5515006 | 0.85 | CCNE2 (0.83) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL7987344 | 0.85 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL5515858 | 0.84 | CCNE2 (0.74) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL8000146 | 0.84 | CCNE2 (0.82) | CCNE2CCNE1CDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291504-B1 | POTENT INHIBITORS OF THE CLASS OF ENZYMES KNOWN AS CYCLIN DEPENDENT KINASES | DUPONT PHARMACEUTICALS COMPANY | 2001-09-18 | — | — | US | claimed |
| US-6291504-B1 | POTENT INHIBITORS OF THE CLASS OF ENZYMES KNOWN AS CYCLIN DEPENDENT KINASES | DUPONT PHARMACEUTICALS COMPANY | 2001-09-18 | — | — | US | disclosed |