Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000655 | 1.00 | NPC1 (0.46) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7997912 | 0.96 | NPC1 (0.48) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7997906 | 0.96 | NPC1 (0.48) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7997672 | 0.95 | NPC1 (0.47) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7997668 | 0.95 | NPC1 (0.47) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7988150 | 0.94 | NPC1 (0.42) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7988155 | 0.94 | NPC1 (0.42) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL8001052 | 0.93 | NPC1 (0.46) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL8001060 | 0.93 | NPC1 (0.46) | NPC1BACE1CYP3A4TDP1KDM4E | |
| SCHEMBL7998888 | 0.92 | NPC1 (0.44) | NPC1BACE1CYP3A4TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |