Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004373 | 0.82 | PARP1 (0.53) | PARP1ARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8004588 | 0.82 | PARP1 (0.49) | PARP1ARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8004541 | 0.80 | AR (0.42) | ARGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7988987 | 0.79 | PARP1 (0.49) | PARP1ARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7997730 | 0.79 | PARP1 (0.49) | PARP1ARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7988937 | 0.79 | PARP1 (0.55) | PARP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7989258 | 0.79 | PARP1 (0.46) | PARP1ARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8001080 | 0.78 | PARP1 (0.62) | PARP1ARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8000846 | 0.76 | PARP1 (0.41) | PARP1AR | |
| SCHEMBL8000842 | 0.76 | PARP1 (0.41) | PARP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |