Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 6/20 | 0.37 |
| ▸ | RORA | P35398 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | RORB | Q92753 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989070 | 0.96 | KDM4E (0.40) | CYP1B1MAPTCYP1A1CYP1A2ABCB1 | |
| SCHEMBL7989010 | 0.96 | KDM4E (0.40) | CYP1B1MAPTCYP1A1CYP1A2ABCB1 | |
| SCHEMBL8001831 | 0.92 | PTPN1 (0.35) | CYP1B1MAPTPTPN1PGRRORA | |
| SCHEMBL7999587 | 0.92 | NPC1 (0.37) | CYP1B1MAPTPTPN1PGRRORA | |
| SCHEMBL7988216 | 0.92 | BACE1 (0.44) | MAPTKDM4EMAPK1ALDH1A1MEN1 | |
| SCHEMBL7988214 | 0.92 | BACE1 (0.44) | MAPTKDM4EMAPK1ALDH1A1MEN1 | |
| SCHEMBL8001085 | 0.90 | KDM4E (0.35) | CYP1B1MAPTPTPN1PGRRORA | |
| SCHEMBL8002113 | 0.90 | MEN1 (0.37) | CYP1B1MAPTPGRRORARORC | |
| SCHEMBL7998295 | 0.90 | KDM4E (0.38) | CYP1B1PTPN1PGRRORARORC | |
| SCHEMBL7997305 | 0.90 | MEN1 (0.37) | CYP1B1MAPTPGRRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |