Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11578116 | 0.87 | TSHR (0.39) | FPR2TDP1TSHR | |
| SCHEMBL11578112 | 0.87 | TSHR (0.39) | FPR2TDP1TSHR | |
| SCHEMBL1658569 | 0.81 | — | — | |
| SCHEMBL1658571 | 0.81 | — | — | |
| SCHEMBL13703080 | 0.81 | — | — | |
| SCHEMBL13703079 | 0.81 | — | — | |
| SCHEMBL9120674 | 0.79 | — | — | |
| SCHEMBL5868311 | 0.77 | TDP1 (0.38) | TDP1TSHR | |
| SCHEMBL3805346 | 0.77 | — | — | |
| SCHEMBL5868309 | 0.77 | TDP1 (0.38) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120799-A2 | METHODS OF TREATING FIBROTIC DISORDERS | PALOMA PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |