Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301406 | 0.93 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL8013118 | 0.91 | AVPR1B (0.54) | AVPR1B | |
| SCHEMBL8024869 | 0.89 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL8021539 | 0.88 | AVPR1B (0.53) | AVPR1B | |
| SCHEMBL8010786 | 0.88 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL8023527 | 0.86 | AVPR1B (0.55) | AVPR1B | |
| SCHEMBL4311828 | 0.85 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL4307066 | 0.84 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL4305060 | 0.84 | AVPR1B (0.56) | AVPR1B | |
| SCHEMBL4302531 | 0.84 | AVPR1B (0.50) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |