Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002011 | 1.00 | NPC1 (0.37) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8002204 | 0.94 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8002208 | 0.94 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7990051 | 0.89 | NPC1 (0.37) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7990055 | 0.89 | NPC1 (0.37) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7998767 | 0.88 | KMT2A (0.42) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7998769 | 0.88 | KMT2A (0.42) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8000137 | 0.84 | MAPT (0.39) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8005181 | 0.83 | KMT2A (0.39) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8005183 | 0.83 | KMT2A (0.39) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |
| WO-1999011634-A1 | TRIAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-11 | — | — | WO | disclosed |