Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007678 | 0.78 | MAPT (0.56) | MAPTTP53LMNATHRBPOLB | |
| SCHEMBL1007931 | 0.75 | SMN1; SMN2 (0.62) | MAPTTP53LMNATHRBPOLB | |
| SCHEMBL1005696 | 0.73 | TDP1 (0.61) | MAPTTP53LMNATHRBPOLB | |
| SCHEMBL1008071 | 0.73 | SMN1; SMN2 (0.62) | MAPTTP53LMNATHRBPOLB | |
| SCHEMBL1895484 | 0.73 | TSHR (0.55) | MAPTTP53LMNATHRBPOLB | |
| SCHEMBL18328416 | 0.72 | POLQ (0.60) | MAPTTP53LMNAPOLBGAA | |
| SCHEMBL18328048 | 0.72 | POLQ (0.60) | MAPTTP53LMNAPOLBGAA | |
| SCHEMBL1007605 | 0.72 | POLB (0.63) | MAPTTP53LMNAPOLBGAA | |
| SCHEMBL1896530 | 0.71 | MAPT (0.69) | MAPTTP53LMNATHRBPOLB | |
| SCHEMBL8000956 | 0.71 | MAPT (0.41) | MAPTTP53LMNATHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |