Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616185 | 0.89 | PDE4A (0.32) | — | |
| Hydrochloric Acid SCHEMBL4200428 | 0.87 | PDE4A (0.31) | — | |
| SCHEMBL3725427 | 0.78 | SOS1 (0.38) | — | |
| SCHEMBL31566610 | 0.78 | SOS1 (0.38) | — | |
| SCHEMBL13689724 | 0.77 | CHRNA7 (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL31566868 | 0.76 | SOS1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL26127261 | 0.75 | SOS1 (0.35) | — | |
| Ethoxycarbonyl Group SCHEMBL27815793 | 0.74 | PDE4A (0.30) | — | |
| Tert-Butyl Formate SCHEMBL28788332 | 0.74 | TDP1 (0.36) | — | |
| SCHEMBL13535037 | 0.72 | TRIM24 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110844-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009108117-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009034380-A1 | PIPERIDINE DERIVATIVES AS AGONISTS OF MUSCARINIC RECEPTORS | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |