Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 10/20 | 0.46 |
| ▸ | FNTB | P49356 | 10/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128682 | 0.92 | MME (0.51) | ACEFNTAFNTBMMEPGGT1B | |
| SCHEMBL6791478 | 0.92 | MME (0.51) | ACEFNTAFNTBMMEPGGT1B | |
| SCHEMBL6791475 | 0.92 | MME (0.51) | ACEFNTAFNTBMMEPGGT1B | |
| SCHEMBL14571186 | 0.90 | FNTA (0.47) | ACEFNTAFNTBMME | |
| SCHEMBL31169703 | 0.90 | ACE (0.44) | ACEFNTAFNTBMMEPTGS1 | |
| SCHEMBL30496770 | 0.89 | MME (0.49) | ACEFNTAFNTBMMEPGGT1B | |
| SCHEMBL30010918 | 0.88 | ACE (0.56) | ACEFNTAFNTBPGGT1BPTGS1 | |
| SCHEMBL29874133 | 0.88 | ACE (0.56) | ACEFNTAFNTBPGGT1BPTGS1 | |
| SCHEMBL30010218 | 0.88 | ACE (0.56) | ACEFNTAFNTBPGGT1BPTGS1 | |
| SCHEMBL30010824 | 0.88 | ACE (0.56) | ACEFNTAFNTBPGGT1BPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776334-A4 | STABLE ANALOGS OF BIOACTIVE PEPTIDES CONTAINING DISULFIDE LINKAGES | MALLINCKRODT MEDICAL INC (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0776334-A1 | STABLE ANALOGS OF BIOACTIVE PEPTIDES CONTAINING DISULFIDE LINKAGES | MALLINCKRODT MEDICAL, INC. (US) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996003429-A1 | STABLE ANALOGS OF BIOACTIVE PEPTIDES CONTAINING DISULFIDE LINKAGES | MALLINCKRODT MEDICAL, INC. (US) | 1996-02-08 | — | — | WO | disclosed |