Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410928 | 0.92 | ADORA1 (0.57) | ADORA1SLC6A3 | |
| SCHEMBL1074200 | 0.86 | ADORA1 (0.55) | ADORA1SLC6A3 | |
| SCHEMBL8002794 | 0.85 | ADORA1 (0.53) | ADORA1SLC6A3 | |
| SCHEMBL12376555 | 0.84 | ADORA1 (0.49) | ADORA1SLC6A3 | |
| SCHEMBL7999946 | 0.83 | ADORA1 (0.49) | ADORA1SLC6A3 | |
| SCHEMBL7999947 | 0.83 | ADORA1 (0.61) | ADORA1SLC6A3 | |
| SCHEMBL8006123 | 0.82 | ADORA1 (0.73) | ADORA1SLC6A3 | |
| SCHEMBL12376548 | 0.80 | ADORA1 (0.49) | ADORA1SLC6A3 | |
| SCHEMBL2281758 | 0.79 | ADORA1 (0.63) | ADORA1SLC6A3 | |
| SCHEMBL12376497 | 0.78 | ADORA1 (0.56) | ADORA1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274299-B1 | HETEROARYL-SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF FOR TREATMENT OF CARDIOVASCULAR DISEASES | BAYER IP GMBH (DE) | 2016-06-15 | — | — | EP | disclosed |
| WO-2009112155-A1 | HETEROARYL-SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF FOR TREATMENT OF CARDIOVASCULAR DISEASES | BAYER SCHERING PHARMA AG (DE) | 2009-09-17 | — | — | WO | disclosed |