Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.70 |
| ▸ | MTOR | P42345 | 14/20 | 0.70 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.66 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.49 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012490 | 0.89 | PIK3CA (0.69) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL8012484 | 0.88 | PIK3CA (0.74) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL8008565 | 0.82 | PIK3CA (1.00) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL1308957 | 0.81 | PIK3CA (1.00) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL8012821 | 0.80 | PIK3CA (0.74) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL1309814 | 0.77 | PIK3CA (0.84) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL18117962 | 0.76 | PIK3CA (0.89) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL1308493 | 0.76 | PIK3CA (0.89) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL18383746 | 0.76 | PIK3CA (0.88) | PIK3CAMTORPIK3R1RICTORRPTOR | |
| SCHEMBL8003292 | 0.76 | PIK3CA (0.80) | PIK3CAMTORPIK3R1PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |