Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 9/20 | 0.55 |
| ▸ | MPC2 | O95563 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000477 | 0.89 | PPARG (0.60) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL6931105 | 0.87 | PPARG (0.70) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL7987726 | 0.85 | PTPN1 (0.59) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL7987911 | 0.84 | PTPN1 (0.79) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL19217676 | 0.82 | FFAR1 (0.61) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL6930674 | 0.82 | FFAR1 (0.61) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL19217845 | 0.82 | FFAR1 (0.61) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL8000591 | 0.82 | PTPN1 (0.57) | FFAR1PPARAPPARGPTPN1CYP3A4 | |
| SCHEMBL7996885 | 0.82 | PPARG (0.61) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL12515224 | 0.81 | FFAR1 (0.69) | FFAR1PPARAPPARGCYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |
| EP-0991632-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | Astra Aktiebolag (SE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057941-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1998-12-23 | — | — | WO | disclosed |