Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431474 | 0.90 | PDE4B (0.55) | PDE4BPDE7APDE3BPDE3A | |
| SCHEMBL3430760 | 0.90 | PDE4B (0.57) | PDE4BPDE7APDE3BPDE3A | |
| SCHEMBL3430500 | 0.89 | PDE4B (0.53) | PDE4B | |
| SCHEMBL8025048 | 0.87 | PDE4B (0.56) | PDE4B | |
| SCHEMBL4524139 | 0.86 | PDE4B (0.57) | PDE4BPDE7APDE3BPDE3A | |
| SCHEMBL3429211 | 0.86 | PDE4B (0.52) | PDE4B | |
| SCHEMBL1316649 | 0.86 | PDE4B (0.52) | PDE4BPDE7APDE3BPDE3A | |
| SCHEMBL4523542 | 0.85 | PDE4B (0.58) | PDE4BPDE7APDE3BPDE3A | |
| SCHEMBL3428989 | 0.85 | PDE4B (0.56) | PDE4B | |
| SCHEMBL8015116 | 0.85 | PDE4B (0.54) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100166-A1 | DUAL PHARMACOPHORES-PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |