⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90072 | 1.00 | — | — | |
| SCHEMBL2760224 | 1.00 | — | — | |
| SCHEMBL14111108 | 0.80 | — | — | |
| SCHEMBL16455039 | 0.80 | — | — | |
| SCHEMBL90066 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL25346768 | 0.78 | KAT6A (0.31) | — | |
| SCHEMBL2917612 | 0.78 | — | — | |
| SCHEMBL24721278 | 0.78 | — | — | |
| SCHEMBL295435 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL25346774 | 0.78 | KAT6A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051341-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | MERCK SHARP & DOHME LLC (US) | 2025-02-13 | — | — | US | disclosed |
| EP-4447971-A2 | PYRAZOLOPYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | Merck Sharp & Dohme LLC (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114157-A2 | PYRAZOLOPYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | MERCK SHARP & DOHME LLC (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2023034812-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2009115685-A1 | NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF. | SANOFI-AVENTIS (FR) | 2009-09-24 | — | — | WO | disclosed |