Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014728 | 1.00 | GAA (0.35) | GAAMAPTPKMMEN1HTT | |
| SCHEMBL8014727 | 1.00 | GAA (0.35) | GAAMAPTPKMMEN1HTT | |
| SCHEMBL8014731 | 1.00 | GAA (0.35) | GAAMAPTPKMMEN1HTT | |
| SCHEMBL8014704 | 0.97 | MAPT (0.37) | GAAMAPTHTTKMT2ATP53 | |
| SCHEMBL8018347 | 0.97 | MAPT (0.37) | GAAMAPTHTTKMT2ATP53 | |
| SCHEMBL8014698 | 0.97 | MAPT (0.37) | GAAMAPTHTTKMT2ATP53 | |
| SCHEMBL8014695 | 0.97 | MAPT (0.37) | GAAMAPTHTTKMT2ATP53 | |
| SCHEMBL8017367 | 0.97 | GAA (0.36) | GAAMAPTPKMMEN1HTT | |
| SCHEMBL8014357 | 0.96 | MEN1 (0.36) | GAAMAPTPKMMEN1HTT | |
| SCHEMBL8021281 | 0.96 | MEN1 (0.36) | GAAMAPTPKMMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149990-A | Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same | CHISSO CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0884302-A1 | CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1998-12-16 | — | — | EP | disclosed |