Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.67 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827612 | 1.00 | GRM2 (0.67) | GRM2MAOAMAOBMEN1MAPT | |
| SCHEMBL2823357 | 0.84 | GRM2 (0.70) | GRM2 | |
| SCHEMBL3744405 | 0.83 | MAOB (0.56) | GRM2MAOAMAOBMEN1MAPT | |
| SCHEMBL2823305 | 0.81 | GRM2 (1.00) | GRM2 | |
| SCHEMBL2824605 | 0.80 | GRM2 (0.76) | GRM2 | |
| SCHEMBL2830372 | 0.79 | GRM2 (0.76) | GRM2 | |
| SCHEMBL8114677 | 0.79 | GRM2 (0.85) | GRM2 | |
| SCHEMBL2823046 | 0.79 | GRM2 (0.90) | GRM2 | |
| SCHEMBL2823430 | 0.79 | GRM2 (0.85) | GRM2 | |
| SCHEMBL2823858 | 0.78 | GRM2 (0.79) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094265-A1 | 3,5-SUBSTITUTED-1,3-OXAZOLIDIN-2-ONE DERIVATIVES | MERCK & CO., INC. (US) | 2009-07-30 | — | — | WO | disclosed |