Benzene

Benzene

SCHEMBL8005754

FC(F)(F)c1c[c]ccc1.c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.52
KIF11 P52732 2/20 0.39
MAPK1 P28482 1/20 0.37
IDO1 P14902 3/20 0.34
TRPV6 Q9H1D0 1/20 0.33
CES2 O00748 1/20 0.33
MGLL Q99685 1/20 0.33
CYP19A1 P11511 1/20 0.32
PTPN1 P18031 1/20 0.32
SRD5A2 P31213 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
IDH2 P48735 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371 0.98 TSHR (0.48) TSHRALDH1A1KIF11MAPK1IDO1
Water SCHEMBL27821326 0.98 TSHR (0.48) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL20526431 0.95 TSHR (0.46) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL3890730 0.95 TSHR (0.46) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL3889885 0.95 TSHR (0.46) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL28824905 0.95 TSHR (0.46) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL3891340 0.95 TSHR (0.46) TSHRALDH1A1KIF11MAPK1IDO1
Magnesium Chloride Anhydrous SCHEMBL28042560 0.89 TSHR (0.41) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL20838399 0.89 TSHR (0.41) TSHRALDH1A1KIF11MAPK1IDO1
SCHEMBL28473627 0.89 TSHR (0.41) TSHRALDH1A1KIF11MAPK1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6110947-A AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS PFIZER INC. (US) 2000-08-29 US disclosed