Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA4 | P22748 | 4/20 | 0.54 |
| ▸ | CA6 | P23280 | 4/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790076 | 0.84 | CA1 (0.60) | CA1CA2CA4CA6HTT | |
| SCHEMBL7999409 | 0.83 | CA1 (0.53) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL4754011 | 0.82 | KDM4E (0.49) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL4726814 | 0.82 | KDM4E (0.49) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL11793897 | 0.81 | CA1 (0.53) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL11795780 | 0.80 | CA1 (0.50) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL19050078 | 0.78 | CA1 (0.63) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL8005760 | 0.78 | CA1 (0.53) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL15874849 | 0.78 | CA1 (0.59) | CA1CA2CA4CA6PTGS1 | |
| SCHEMBL7486281 | 0.78 | CA1 (0.59) | CA1CA2CA4CA6PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-2000016760-A2 | NEW USE OF PROSTAGLANDIN E2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-30 | — | — | WO | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |