Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410903 | 0.92 | ADORA1 (0.53) | ADORA1SLC6A3 | |
| SCHEMBL1076310 | 0.85 | ADORA1 (0.61) | ADORA1SLC6A3 | |
| SCHEMBL2282177 | 0.84 | ADORA1 (0.73) | ADORA1SLC6A3 | |
| SCHEMBL8002243 | 0.84 | ADORA1 (0.55) | ADORA1SLC6A3 | |
| SCHEMBL1076183 | 0.84 | ADORA1 (0.57) | ADORA1SLC6A3 | |
| SCHEMBL8001636 | 0.84 | ADORA1 (0.51) | ADORA1SLC6A3 | |
| SCHEMBL8005108 | 0.83 | ADORA1 (0.52) | ADORA1SLC6A3 | |
| SCHEMBL924730 | 0.82 | ADORA1 (0.56) | ADORA1SLC6A3 | |
| SCHEMBL924731 | 0.82 | ADORA1 (0.56) | ADORA1SLC6A3 | |
| SCHEMBL2277947 | 0.81 | ADORA1 (0.59) | ADORA1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274299-B1 | HETEROARYL-SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF FOR TREATMENT OF CARDIOVASCULAR DISEASES | BAYER IP GMBH (DE) | 2016-06-15 | — | — | EP | disclosed |
| US-8426602-B2 | Heteroaryl-substituted dicyanopyridines and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-23 | — | — | US | disclosed |
| WO-2009112155-A1 | HETEROARYL-SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF FOR TREATMENT OF CARDIOVASCULAR DISEASES | BAYER SCHERING PHARMA AG (DE) | 2009-09-17 | — | — | WO | disclosed |