Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017067 | 0.91 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL8023735 | 0.89 | SRD5A1 (0.60) | SRD5A2SRD5A1AR | |
| SCHEMBL8017035 | 0.88 | SRD5A2 (0.44) | SRD5A2SRD5A1AR | |
| SCHEMBL8016674 | 0.84 | SRD5A2 (0.60) | SRD5A2SRD5A1AR | |
| SCHEMBL8016224 | 0.84 | SRD5A1 (0.61) | SRD5A2SRD5A1AR | |
| SCHEMBL8023753 | 0.83 | SRD5A1 (0.64) | SRD5A2SRD5A1 | |
| SCHEMBL8006797 | 0.81 | SRD5A2 (0.55) | SRD5A2SRD5A1 | |
| SCHEMBL8016710 | 0.81 | SRD5A2 (0.64) | SRD5A2SRD5A1AR | |
| SCHEMBL8019047 | 0.81 | SRD5A2 (0.51) | SRD5A2SRD5A1AR | |
| SCHEMBL8006808 | 0.80 | SRD5A1 (0.62) | SRD5A2SRD5A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664812-B1 | 17-BETA-ARYL ESTER CARBOXYLATES OF 4-AZA-5-ALPHA-ANDROSTANE-3-ONES | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | claimed |
| EP-0664812-B1 | 17-BETA-ARYL ESTER CARBOXYLATES OF 4-AZA-5-ALPHA-ANDROSTANE-3-ONES | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5278159-A | Steroid enzyme inhibitor | MERCK & CO., INC. (US) | 1994-01-11 | — | — | US | disclosed |