SCHEMBL8007480

SCHEMBL8007480

O=C(O)c1c(F)c(F)c(C(c2c(F)c(F)c(C(=O)O)c(C(=O)O)c2F)(C(F)(F)F)C(F)(F)F)c(F)c1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ASPH Q12797 1/20 0.31
KDM8 Q8N371 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29963060 1.00 TSHR (0.32) TSHRSMN1; SMN2KDM4EASPHKDM8
SCHEMBL28710498 0.93 SMN1; SMN2 (0.33) TSHRSMN1; SMN2KDM4EASPHKDM8
SCHEMBL8466685 0.82 SMN1; SMN2 (0.47) TSHRSMN1; SMN2
SCHEMBL8004141 0.82 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL8006569 0.82 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL29962886 0.78 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL16268474 0.78 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL29140656 0.76
SCHEMBL29671481 0.76 MEN1 (0.33) SMN1; SMN2
SCHEMBL9140462 0.75 TSHR (0.31) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111095440-B Insulating composition containing silica 日产化学株式会社 2022-01-04 CN disclosed
CN-112566985-A Coloring composition, cured film, pattern forming method, color filter, solid-state imaging element, and image display device 富士胶片株式会社 2021-03-26 CN disclosed
CN-111095440-A Insulating composition containing silica 日产化学株式会社 2020-05-01 CN disclosed
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
EP-3004211-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE Ricoh Company, Ltd. (JP) 2016-04-13 EP disclosed
US-20150203652-A1 METAL FINE-PARTICLE COMPOSITE AND METHOD FOR FABRICATING THE SAME TOKYO INST TECH (JP) 2015-07-23 US disclosed
WO-2014192665-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICOH COMPANY, LTD. (JP) 2014-12-04 WO disclosed
EP-2579022-A1 METAL MICROPARTICLE COMPOSITE AND METHOD FOR PRODUCING THE SAME Tokyo Institute of Technology (JP) 2013-04-10 EP disclosed
US-20130071619-A1 METAL FINE-PARTICLE COMPOSITE AND METHOD FOR FABRICATING THE SAME NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2013-03-21 US disclosed
US-6048986-A DEHYDRATION OF DIFLUOROPYROMELLITIC ACID TO FORM DIFLUOROPYROMELLITIC DIANHYDRIDE NIPPON TELEGRAPH AND TELEPHONE CORP. (JP) 2000-04-11 US disclosed
EP-0623830-B1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH & TELEPHONE (JP) 1999-08-18 EP disclosed
US-5901259-A Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1999-05-04 US disclosed
US-5849934-A Method for preparing aromatic compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1998-12-15 US disclosed
US-5750731-A POLYIMIDE ANHYDRIDE MONOMERS NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-05-12 US disclosed
US-5694496-A WAVEGUIDE COMPRISING AN AROMATIC FLUORO-POLYIMIDE; HEAT RESISTANCE, FLEXIBILITY, WATERPROOFING, STRENGTH NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1997-12-02 US disclosed
EP-0480266-B1 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH & TELEPHONE (JP) 1996-06-26 EP disclosed
EP-0623830-A1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-11-09 EP disclosed
US-5233018-A Heat resistance and low optical transmission loss in the near-infrared region; integrated circuits NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1993-08-03 US disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed