Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 19/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 18/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 18/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 18/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 18/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 18/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 18/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302083 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL8009252 | 0.76 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16566468 | 0.76 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16580910 | 0.76 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL1365287 | 0.76 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16302027 | 0.75 | HDAC1 (0.44) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16302037 | 0.74 | HDAC6 (0.55) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL7997961 | 0.74 | HDAC6 (0.55) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL11993890 | 0.72 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16302032 | 0.72 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137503-A1 | HDAC INHIBITORS AND USES THEREOF | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |