SCHEMBL8008558

SCHEMBL8008558

CC(=O)NC(C)S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4993792 0.78 FOLH1 (0.37)
SCHEMBL26505358 0.77
SCHEMBL13778719 0.77
SCHEMBL8379073 0.75
SCHEMBL28072275 0.75
SCHEMBL13692 0.73
SCHEMBL3392039 0.73 KDM4E (0.50)
SCHEMBL14157901 0.73 TRPV1 (0.46)
SCHEMBL5501813 0.73
SCHEMBL19485944 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116515915-A Adipic acid ester or thioester synthesis 基因组股份公司 2023-08-01 CN claimed
EP-0432000-B1 REDUCING COMPOSITION FOR PERMANENT HAIRWAVING, COMPRISING AS REDUCING AGENT AN AMINO-MERCAPTOALKYLAMIDE OR ONE OF ITS SALTS, AND ITS USE IN A PROCESS FOR PERMANENT HAIRWAVING L'OREAL (FR) 1993-08-11 EP claimed
EP-0432000-A1 Reducing composition for permanent hairwaving, comprising as reducing agent an amino-mercaptoalkylamide or one of its salts, and its use in a process for permanent hairwaving L'OREAL (FR) 1991-06-12 EP claimed
US-RE50030-E1 Methods to treat lymphoplasmacytic lymphoma DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-07-02 US disclosed
CN-116515915-A Adipic acid ester or thioester synthesis 基因组股份公司 2023-08-01 CN disclosed
EP-4215530-A1 ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2023-07-26 EP disclosed
CN-109468348-B Adipic acid ester or thioester synthesis 基因组股份公司 2023-05-16 CN disclosed
US-10988477-B2 GCN2 inhibitors and uses thereof MERCK PATENT GMBH (DE) 2021-04-27 US disclosed
WO-2019014315-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. (US) 2019-01-17 WO disclosed
US-9872918-B2 Hydroxyl-polymer-drug-protein conjugates MERSANA THERAPEUTICS, INC. (US) 2018-01-23 US disclosed
US-6114364-A 2-((SUBSTITUTED)ALKYL(THIO, SULFONYL, OR SULFOXY)METHYL), 3-(CARBOXYL OR ALIPHATIC HYDROCARBONYL)CYCLOPENTAN-1-ONE DERIVATIVES, EXCEPT CYSTACYCLIN; USE AS NEURON DIFFERENTIATION ACCELERATOR NIPPON KAYAKU CO., LTD. (JP) 2000-09-05 US disclosed
US-5306731-A Treating glaucoma by administering to eye molecules which increase outflow of aqueous humor in conjunction with masking agent to reduce side effects MASSACHUSETTS EYE AND EAR INFIRMARY (US) 1994-04-26 US disclosed
EP-0575524-A1 METHOD AND PRODUCTS FOR TREATING THE EYE MASSACHUSETTS EYE &amp; EAR INFIRMARY (US) 1993-12-29 EP disclosed
EP-0432000-B1 REDUCING COMPOSITION FOR PERMANENT HAIRWAVING, COMPRISING AS REDUCING AGENT AN AMINO-MERCAPTOALKYLAMIDE OR ONE OF ITS SALTS, AND ITS USE IN A PROCESS FOR PERMANENT HAIRWAVING L'OREAL (FR) 1993-08-11 EP disclosed
WO-1993010142-A1 NEW LUPANE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1993-05-27 WO disclosed
EP-0542622-A1 New lupane derivatives, a process for their production and pharmaceutical compositions containing them Aventis Pharma S.A. (FR) 1993-05-19 EP disclosed
EP-0432000-A1 Reducing composition for permanent hairwaving, comprising as reducing agent an amino-mercaptoalkylamide or one of its salts, and its use in a process for permanent hairwaving L'OREAL (FR) 1991-06-12 EP disclosed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP disclosed
EP-0073451-A2 Carbapenam compound and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-03-09 EP disclosed
US-4153714-A BACTERICIDES AMINO ACID DERIVATIVE ANTIBIOTICS BEECHAM GROUP LIMITED (GB) 1979-05-08 US disclosed