Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.53 |
| ▸ | KDM1A | O60341 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302090 | 1.00 | HDAC6 (0.53) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL12460629 | 0.87 | HDAC1 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL11993890 | 0.87 | HDAC1 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL16302032 | 0.87 | HDAC1 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL7997961 | 0.87 | HDAC6 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL16302037 | 0.87 | HDAC6 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL16302073 | 0.86 | HDAC1 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL16302045 | 0.85 | HDAC1 (0.49) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL8011347 | 0.85 | HDAC1 (0.49) | HDAC6HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL1366962 | 0.85 | HDAC1 (0.53) | HDAC6HDAC1HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137503-A1 | HDAC INHIBITORS AND USES THEREOF | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |