Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671192 | 1.00 | CES1 (0.59) | CES1SRD5A1CYP2A6MAOAMAOB | |
| SCHEMBL11671185 | 1.00 | CES1 (0.59) | CES1SRD5A1CYP2A6MAOAMAOB | |
| Dihydrophenanthrene SCHEMBL155991 | 0.84 | CES1 (0.68) | CES1SRD5A1CYP2A6MAOAMAOB | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.84 | CES1 (0.68) | CES1SRD5A1CYP2A6MAOAMAOB | |
| Dihydrophenanthrene SCHEMBL30297028 | 0.84 | CES1 (0.68) | CES1SRD5A1CYP2A6MAOAMAOB | |
| SCHEMBL110502 | 0.83 | CES1 (0.48) | CES1SRD5A1CYP2A6MAOAMAOB | |
| Dihydrophenanthrene SCHEMBL28858771 | 0.81 | CES1 (0.65) | CES1SRD5A1CYP2A6MAOAMAOB | |
| SCHEMBL30436624 | 0.81 | CES1 (0.65) | CES1SRD5A1CYP2A6MAOAMAOB | |
| Dihydrophenanthrene SCHEMBL28876918 | 0.81 | CES1 (0.65) | CES1SRD5A1CYP2A6MAOAMAOB | |
| SCHEMBL16886044 | 0.81 | CYP19A1 (0.53) | CES1SRD5A1MAOAMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107163246-A | Reversible thermal contraction polyarylamide of backbone chain type octatomic ring containing dibenzo structure and preparation method thereof | 复旦大学 | 2017-09-15 | — | — | CN | claimed |
| CN-107163246-A | Reversible thermal contraction polyarylamide of backbone chain type octatomic ring containing dibenzo structure and preparation method thereof | 复旦大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-103012292-B | Synthetic method of dibenzanthracene [b,f][1,2] diazocine | UNIV CHANGZHOU | 2014-12-31 | — | — | CN | disclosed |
| CN-101970572-B | Photocurable composition | SEKISUI CHEMICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-103012292-A | Synthetic method of dibenzanthracene [b,f][1,2] diazocine | UNIV CHANGZHOU | 2013-04-03 | — | — | CN | disclosed |
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |
| CN-1380883-A | Novel derivatives and analogues of galanthamine | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2002-11-20 | — | — | CN | disclosed |
| CN-1064354-C | Antimicrobial 5- (N-heterosubstituted amino) quinolones and pharmaceutical compositions | AMERICAN CYANAMID CO (US) | 2001-04-11 | — | — | CN | disclosed |
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |
| CN-1038839-C | Process for preparation of cyclic amine compounds | EISAI CO LTD (JP) | 1998-06-24 | — | — | CN | disclosed |
| CN-1164856-A | Novel alkylamino derivatives as sigma 2 selective ligands | MITSUBISHI CHEM CORP (JP) | 1997-11-12 | — | — | CN | disclosed |
| CN-1034015-C | Process to prepare cycloamine compounds | EISAI CO LTD (JP) | 1997-02-12 | — | — | CN | disclosed |
| CN-1106802-A | Tricyclic benzazepines (aza *) vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1995-08-16 | — | — | CN | disclosed |
| CN-1104211-A | Tricyclic condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-06-28 | — | — | CN | disclosed |
| CN-1103534-A | Compound with antipsychotic effect | MEIJI SEIKA CO (JP) | 1995-06-07 | — | — | CN | disclosed |
| CN-1024547-C | Preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| CN-1073939-A | A kind of preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1993-07-07 | — | — | CN | disclosed |
| CN-1071417-A | The preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1993-04-28 | — | — | CN | disclosed |
| CN-1030752-A | Preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1989-02-01 | — | — | CN | disclosed |