Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA6 | P23280 | 5/20 | 0.52 |
| ▸ | CA7 | P43166 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA5A | P35218 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008362 | 1.00 | CA12 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL6251213 | 0.91 | CA12 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL10939589 | 0.88 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL2422624 | 0.85 | — | — | |
| SCHEMBL11905533 | 0.85 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5960649 | 0.85 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL18979142 | 0.83 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL16341215 | 0.83 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL28465765 | 0.83 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL28158597 | 0.80 | CA12 (0.39) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100308-A | COPOLYMERIZING A DI- OR POLYISOCYANATES WITH A POLYETHER POLYOLS BASED ON AROMATIC AMINES WITH CHAIN EXTENDERS AND/OR CROSSLINKERS IN THE PRESENCE OF BLOWING AGENTS TO FORM THE RIGID POLYETHERURETHANE FOAMS; USE AS INSULATION MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| US-5205956-A | Fluorocarbon blowing agent | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |