Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009758 | 1.00 | POLB (0.55) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL9413338 | 0.91 | POLB (0.51) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL30193123 | 0.91 | POLB (0.51) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL9413339 | 0.91 | POLB (0.51) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL1494020 | 0.88 | POLB (0.48) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL6193768 | 0.85 | BACE1 (0.60) | POLBMEN1KMT2AMAPTBACE1 | |
| SCHEMBL6193762 | 0.85 | BACE1 (0.60) | POLBMEN1KMT2AMAPTBACE1 | |
| SCHEMBL6195510 | 0.85 | BACE1 (0.49) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL6195516 | 0.85 | BACE1 (0.49) | POLBCTSVCTSLMEN1KMT2A | |
| SCHEMBL8010330 | 0.83 | TLR4 (0.54) | POLBCTSVCTSLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6228093-A | — | — | None | — | — | JP | disclosed |
| US-6160127-A | Process for the preparation of substituted indoles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| EP-0972763-A1 | Process for the preparation of substituted indoles | Bristol-Myers Squibb Company (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0598383-B1 | Process for the preparation of 5,6-diacetoxyindole | BRISTOL MYERS SQUIBB CO (US) | 1999-02-03 | — | — | EP | disclosed |
| JP-H06228093-A | PREPARATION OF 5,6-DIACETOXYINDOLE | BRISTOL MYERS SQUIBB CO | 1994-08-16 | — | — | JP | disclosed |
| EP-0598383-A1 | Process for the preparation of 5,6-diacetoxyindole | Bristol-Myers Squibb Company (US) | 1994-05-25 | — | — | EP | disclosed |
| US-5262546-A | Process for the preparation of 5,6-diacetoxyindole | CLAIROL, INC. (US) | 1993-11-16 | — | — | US | disclosed |