SCHEMBL8009874

SCHEMBL8009874

CCCCCCC1CN(c2cccc(F)c2N)C(=O)O1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2828077 0.89 GRM2 (0.82) GRM2
SCHEMBL2825439 0.89 GRM2 (1.00) GRM2
SCHEMBL2821961 0.85 GRM2 (0.76) GRM2
SCHEMBL2826003 0.84 GRM2 (0.74) GRM2
SCHEMBL2821817 0.81 GRM2 (0.72) GRM2
SCHEMBL2823679 0.81 GRM2 (0.69) GRM2
SCHEMBL2823516 0.81 GRM2 (0.72) GRM2
SCHEMBL2823060 0.80 GRM2 (0.74) GRM2
SCHEMBL2855352 0.80 GRM2 (0.74) GRM2
SCHEMBL2824041 0.79 GRM2 (0.73) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009094265-A1 3,5-SUBSTITUTED-1,3-OXAZOLIDIN-2-ONE DERIVATIVES MERCK & CO., INC. (US) 2009-07-30 WO disclosed