Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9436976 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL7983250 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL7527293 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL9004283 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL15103409 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL10379498 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL9001699 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL7996596 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL9013971 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 | |
| Bicarbonate SCHEMBL9437102 | 1.00 | CA4 (0.50) | CA4CA1CA2CA9FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107354041-A | It is a kind of to be used to remove the cleaning agent to remove grease | 南通科星化工有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-102418260-B | Calamine alginate fiber fabrics pretreatment, dyeing and finishing technology | FUJIAN ZHONGHE CO LTD | 2013-07-03 | — | — | CN | claimed |
| CN-102418260-A | Pretreatment, dyeing and finishing process of calamine alginate fiber fabric | FUJIAN ZHONGHE CO LTD | 2012-04-18 | — | — | CN | claimed |
| CN-107354041-A | It is a kind of to be used to remove the cleaning agent to remove grease | 南通科星化工有限公司 | 2017-11-17 | — | — | CN | disclosed |
| US-20150174277-A1 | COMPOSITIONS FOR VISUALIZATION OF CLEANING EFFICACY AND PRODUCT COVERAGE | LARY JR ROBERT YALE (US) | 2015-06-25 | — | — | US | disclosed |
| CN-102418260-A | Pretreatment, dyeing and finishing process of calamine alginate fiber fabric | FUJIAN ZHONGHE CO LTD | 2012-04-18 | — | — | CN | disclosed |
| EP-0914411-A4 | N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS | HAMPSHIRE CHEMICAL CORP (US) | 2000-06-07 | — | — | EP | disclosed |
| EP-0914411-A1 | N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS | HAMPSHIRE CHEMICAL CORP. (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997040129-A1 | N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS | HAMPSHIRE CHEMICAL CORP. (US) | 1997-10-30 | — | — | WO | disclosed |