SCHEMBL8010019

SCHEMBL8010019

COc1c(F)c(F)c(-c2c(F)c(F)c(Cl)c(F)c2F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11017584 0.87 HSD17B10 (0.33) HSD17B10
SCHEMBL1711725 0.87 HSD17B10 (0.47) HSD17B10
SCHEMBL12965347 0.84 HSD17B10 (0.45) HSD17B10
SCHEMBL22164291 0.78 HSD17B10 (0.39) HSD17B10
SCHEMBL3763099 0.78 HSD17B10 (0.41) HSD17B10
SCHEMBL20885106 0.78
SCHEMBL12451104 0.77 HSD17B10 (0.41) HSD17B10
SCHEMBL8072958 0.76 HSD17B10 (0.34) HSD17B10
SCHEMBL21103403 0.75 HSD17B10 (0.40) HSD17B10
SCHEMBL2728186 0.75 HSD17B10 (0.40) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6129863-A Clean generation of a perfluoroaryl grignard reagent ALBEMARLE CORPORATION (US) 2000-10-10 US disclosed
WO-2000035923-A1 CLEAN GENERATION OF A PERFLUOROARYL GRIGNARD REAGENT ALBEMARLE CORPORATION (US) 2000-06-22 WO disclosed