SCHEMBL8010072

SCHEMBL8010072

CCc1ccc(C(C)=NOCc2ccccc2)cc1OCC(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.47
PPARA Q07869 10/20 0.47
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
S1PR1 P21453 2/20 0.43
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
PPARD Q03181 1/20 0.41
SMPD1 P17405 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
LTB4R Q15722 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8009797 1.00 PPARG (0.47) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8026075 0.88 PPARG (0.48) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8020889 0.88 PPARG (0.48) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8024276 0.87 NPC1 (0.49) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8024277 0.87 NPC1 (0.49) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8026206 0.80 PPARG (0.45) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8019905 0.79 PPARG (0.45) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8019904 0.79 PPARG (0.45) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8026204 0.79 PPARG (0.44) PPARGPPARANPC1RAB9AS1PR1
SCHEMBL8026203 0.79 PPARG (0.44) PPARGPPARANPC1RAB9AS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975587-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
WO-1998043949-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-08 WO disclosed