Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 8/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380892 | 0.84 | HTT (0.52) | HTT | |
| SCHEMBL10589601 | 0.84 | HTT (0.52) | HTT | |
| SCHEMBL8013574 | 0.81 | TACR1 (0.46) | TACR1MEN1LMNAHTR1EHTT | |
| SCHEMBL8017603 | 0.80 | TACR1 (0.54) | TACR1 | |
| SCHEMBL9002757 | 0.78 | TACR1 (0.44) | TACR1 | |
| SCHEMBL20863897 | 0.78 | PSMB9 (0.52) | MMP3MMP1MMP2PSMB9KMT2A | |
| SCHEMBL15095228 | 0.77 | KMT2A (0.45) | MMP3MMP1PSMB9KMT2A | |
| SCHEMBL10646776 | 0.76 | KMT2A (0.53) | PSMB9MEN1LMNAKMT2A | |
| SCHEMBL10646770 | 0.76 | KMT2A (0.53) | PSMB9MEN1LMNAKMT2A | |
| SCHEMBL31385580 | 0.76 | MEN1 (0.49) | MEN1LMNAHTR1EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127144-A | PRODUCING HETEROLOGOUS PROTEINS BY INCUBATING STREPTOMYCES CELL TRANSFORMED WITH NUCLEIC ACID EXPRESSION CONSTRUCT IN PRESENCE OF PEPTIDE-SUSBSTITUTED CHLOROMETHYLKETONE AMINOPEPTIDASE INHIBITOR HAVING DEFINED STRUCTURE | CANGENE CORPORATION (CA) | 2000-10-03 | — | — | US | disclosed |
| EP-0731841-A1 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | Cangene Corporation (CA) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995017512-A2 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | CANGENE CORPORATION (CA) | 1995-06-29 | — | — | WO | disclosed |