Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.57 |
| ▸ | MTOR | P42345 | 9/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012368 | 0.94 | PIK3CA (0.60) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL8015931 | 0.91 | PIK3CA (0.62) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL7999518 | 0.84 | PIK3CA (0.74) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL8008731 | 0.81 | PIK3CB (0.76) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL993492 | 0.80 | PIK3CB (0.76) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL8012490 | 0.79 | PIK3CA (0.69) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL8010379 | 0.78 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL1308957 | 0.76 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL8009906 | 0.75 | PIK3CA (0.71) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL12950149 | 0.73 | PIK3CB (1.00) | PIK3CAMTORPIK3R1PIK3CBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |