Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 3/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214614 | 1.00 | CYP2C9 (0.39) | CYP2C9CYP2C19HIF1AEPHX1CYP2D6 | |
| SCHEMBL1915638 | 0.98 | CYP2C9 (0.41) | CYP2C9CYP2C19HIF1AEPHX1CYP2D6 | |
| SCHEMBL1915636 | 0.98 | CYP2C9 (0.41) | CYP2C9CYP2C19HIF1AEPHX1CYP2D6 | |
| SCHEMBL24049739 | 0.97 | BTK (0.39) | CYP2C9CYP2C19HIF1AEPHX1CYP2D6 | |
| SCHEMBL22035440 | 0.97 | BTK (0.39) | CYP2C9CYP2C19HIF1AEPHX1CYP2D6 | |
| SCHEMBL25409678 | 0.97 | BTK (0.39) | CYP2C9CYP2C19HIF1AEPHX1CYP2D6 | |
| SCHEMBL2587506 | 0.93 | STING1 (0.38) | CYP2D6HDAC1HDAC6GAAHDAC3 | |
| SCHEMBL2587507 | 0.93 | STING1 (0.38) | CYP2D6HDAC1HDAC6GAAHDAC3 | |
| SCHEMBL15483715 | 0.93 | STING1 (0.38) | CYP2D6HDAC1HDAC6GAAHDAC3 | |
| SCHEMBL20221370 | 0.87 | EPHX1 (0.37) | EPHX1CYP2D6BTKHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363119-A1 | PROTEASOME INHIBITORS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2021-11-25 | — | — | US | disclosed |
| WO-2000031020-A1 | IMPROVED GAMMA AMINO BUTYRIC ACID ANALOGS | WARNER-LAMBERT COMPANY (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363119-A1 | PROTEASOME INHIBITORS | TP53, CDKN1A, PSME1 | CYP2C9 4309/4885CYP2C19 4237/4885HIF1A 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.